Mood disorders: Clinical practice guidelines and associated resources

Clinical practice guideline for the treatment of mood disorders (2020) [PDF; 9 MB]
Guidance on the clinical management of depressive and bipolar disorders, specifically focusing on diagnosis and treatment strategies.

The 2020 guideline builds on the previous 2015 Clinical Practice Guideline (linked here for reference purposes) and maintains its joint focus on both depressive and bipolar disorders.

Access further guidance on specific treatments for mood disorders in the following documents developed by the College:


Key practice points

The 2020 guideline builds on the previous guidelines (issued in 2015) and provides up-to-date recommendations and guidance within an evidence-based framework, supplemented by expert clinical consensus. 

The 2020 guideline: 

  • discusses the diagnosis and management of both depressive and bipolar disorders, recognising that these have increasingly been conceptualised as part of a spectrum
  • illustrates step-by-step the clinical management of mood disorders
  • provides guidance on the management of psychiatric comorbidities, including comorbid anxiety and comorbid substance use
  • considers the clinical management of mood disorders with complex presentations and in special populations. 

Associated resources 

Webinar recordings and e-learning modules

Delivered via the RANZCP's e-learning platform, Learnit.  Member sign-in is required to access the modules.


New Clinical Guidelines for Mood Disorders: Management of Major Depressive Disorder and Treatment Non-Response


New Clinical Guidelines for Mood Disorders: Classification, Diagnosis, Assessment and Formulation


Community resources


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